This study investigated the effect of various stacking sequences on the mechanical and acoustic characteristics of hemp and kenaf fibers reinforced hybrid composites. The mechanical study was done by using universal testing machine and izod imact tester. Further, acoustic study was done by using impendence tube method. Hemp/kenaf/kenaf/hemp hybrid laminates outperformed the other composites in terms of tensile strength, flexural strength and impact strength. In the mono reinforcements, hemp/epoxy composites demonstrated superior mechanical characteristics than the epoxy matrix and kenaf/epoxy composites. However, hybrid composites have superior mechanical behavior compared to pure composites. From the acoustic results revealed that the pure hemp and kenaf/hemp/hemp/kenaf hybrid composites exhibited highest sound transmission loss level at lowest and highest frequency region. The best mechanical characteristics of hybrid composites will be suggested for use in automobile door panels. Also, the optimal sound transmission coefficient values signifying their appropriateness for use in applications that encompass many frequency bands.