Understanding the compositional dependence of glass formation in Cu-Zr alloys remains essential for the rational development of bulk metallic glasses. In this work, a systematic investigation is carried out across a broad compositional range to examine the correlations among thermodynamic stabilization, atomic packing characteristics, and kinetic resistance to crystallization. Parameters related to chemical interactions and packing efficiency are analyzed together with viscosity-based kinetic modeling and transformation behavior derived from time-temperature relationships. In parallel, previously reported Voronoi analyses and structural studies are correlated with the present thermodynamic and kinetic trends to interpret the evolution of local atomic ordering with composition. The results indicate that the glass-formation ability is highly sensitive to composition and is enhanced within an intermediate Cu-rich region from
55-65 at.%. Alloys in this range exhibit favorable stabilization of the liquid state, reduced atomic diffusivity, delayed crystallization kinetics, and an increased population of densely packed icosahedral-type local structures. Together, these factors hinder long-range atomic rearrangements, thereby improving resistance to crystallization and promoting glass formation. The integrated compositional analysis presented here offers additional insight into the combined roles of thermodynamic stabilization, structural ordering, and crystallization kinetics in metallic glass formation.