In this paper, the authors have analyzed the effect of valve stiction on multivariable TITO process. Valve stiction is a major nonlinearity in process industries, often causing oscillations and poor control performance. The majority of research focuses on stiction detection in single-input single-output (SISO) systems, although loop interactions present extra difficulties for multivariable processes. In this work, valve stiction in a closedloop, two-input, two-output (TITO) process is examined. Three scenarios are studied: stiction in Loop 1 while Loop 2 remains linear, stiction in Loop 2 while Loop 1 remains linear, and stiction in both loops. For each scenario, the controller output (CO), manipulated variable (MV), and process variable (PV) are recorded for both loops to examine the propagation of nonlinear effects. Performance is evaluated through correlations between COs and MVs. The results show that stiction in one loop not only affects its own performance but also causes oscillations and performance degradation in the interacting loop, emphasizing the need for MIMO aware stiction diagnosis and compensation.